In our recent question and also answer, we discuss the safety and security considerations when combining alcohol with fluconazole.

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patty asked

I take it a one day fluconazole dose, 150 mg pill, for a yeast infection. Is the OK come drink alcohol 2 days later? how long before it pipeline your system?


There is no medicine interaction between fluconazole and alcohol, however it normally is not recommended come drink alcohol when recovering indigenous an infection. Alcohol has the propensity to decrease immune function, at least acutely (1). In addition, it can potentially worsen medication next effects, including:

NauseaDiarrheaUpset stomach

What Is Fluconazole?

Fluconazole, likewise known through the brand name Diflucan, is a systemic anti-fungal that is commonly used because that yeast infections and oral thrush infections. It is typically well tolerated but has been known to cause headache, nausea and ab pain.

An interesting characteristic the fluconazole is its capability to eradicate many fungal infections, consisting of vaginal fungal infections, in a single dose. This is due to how fluconazole works and also the fairly long half life of the drug.

How walk Fluconazole Work?

Fluconazole functions by inhibiting the synthetic of a crucial component (ergosterol) the the fungal cell membrane. A single dose the fluconazole has actually a reported fifty percent life that 30-50 hours(2). In general, a drug takes about 5 fifty percent lives come be totally metabolized and eliminated native the body. This essentially method that the medicine is existing and energetic in the body because that 6 to 10 days! that is why a solitary dose is reliable for eradicating infections.

After a solitary dose, symptoms have tendency to get much better after 1 come 3 days and the bulk of infections room cleared in 7 to 10 days. The clinical cure rate with single doses the fluconazole is roughly 69%, i m sorry is why occasionally doctors will certainly recommend taking a second dose the fluconazole 7 days after the early dose.

See more: What Does Letra Mean In Spanish ? English Translation Of “Letra”

Problems through Alcohol and Fluconazole

In for to taking alcohol ~ fluconazole administration, over there is no drug communication as pointed out above. However, if you are experiencing any type of symptoms native medication use such together nausea or abdominal muscle pain, alcohol may worsen those next effects. Fluconazole big in the body for a considerable period of time, 6 come 10 days. If you wish to fully avoid alcohol when the medicine is present, girlfriend would need to wait that period of time.